Magnesium acts as a natural calcium channel blocker. High-dose supplementation with medications like amlodipine, diltiazem may cause excessive blood pressure lowering, dizziness, or fatigue.
Recommendation
Start magnesium at lower doses and monitor BP if on CCBs.
Timing
Monitor blood pressure when starting magnesium
Sources
— Magnesium Research
— PMID: 22961193
Frequently Asked Questions
Can I take calcium channel blockers and magnesium together?
Magnesium may enhance BP lowering effect. Start magnesium at lower doses and monitor BP if on CCBs.
How should I time calcium channel blockers and magnesium?
Monitor blood pressure when starting magnesium
Is this interaction dangerous?
This interaction is rated “Caution” by Formulate. Magnesium acts as a natural calcium channel blocker. High-dose supplementation with medications like amlodipine, diltiazem may cause excessive blood pressure lowering, dizziness, or fatigue.
Want to check your whole stack?
The free checker lets you add any combination of supplements and medications at once. Formulate's desktop app goes further — every stack change surfaces interaction alerts automatically.