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calcium channel blockers and magnesium

Magnesium may enhance BP lowering effect

What's happening

Magnesium acts as a natural calcium channel blocker. High-dose supplementation with medications like amlodipine, diltiazem may cause excessive blood pressure lowering, dizziness, or fatigue.

Recommendation

Start magnesium at lower doses and monitor BP if on CCBs.

Timing

Monitor blood pressure when starting magnesium

Sources

  • Magnesium Research
  • PMID: 22961193

Frequently Asked Questions

Can I take calcium channel blockers and magnesium together?

Magnesium may enhance BP lowering effect. Start magnesium at lower doses and monitor BP if on CCBs.

How should I time calcium channel blockers and magnesium?

Monitor blood pressure when starting magnesium

Is this interaction dangerous?

This interaction is rated “Caution” by Formulate. Magnesium acts as a natural calcium channel blocker. High-dose supplementation with medications like amlodipine, diltiazem may cause excessive blood pressure lowering, dizziness, or fatigue.

Want to check your whole stack?

The free checker lets you add any combination of supplements and medications at once. Formulate's desktop app goes further — every stack change surfaces interaction alerts automatically.

Medical disclaimer. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.