Skip to main content

magnesium and nsaids

NSAIDs may reduce magnesium levels

What's happening

Non-steroidal anti-inflammatory drugs (ibuprofen, naproxen) can increase renal magnesium excretion and reduce intestinal absorption with long-term use.

Recommendation

Consider magnesium supplementation if using NSAIDs regularly.

Timing

Take magnesium separately from NSAIDs

Sources

  • Magnesium Research
  • PMID: 18385835

Frequently Asked Questions

Can I take magnesium and nsaids together?

NSAIDs may reduce magnesium levels. Consider magnesium supplementation if using NSAIDs regularly.

How should I time magnesium and nsaids?

Take magnesium separately from NSAIDs

Is this interaction dangerous?

This interaction is rated “Caution” by Formulate. Non-steroidal anti-inflammatory drugs (ibuprofen, naproxen) can increase renal magnesium excretion and reduce intestinal absorption with long-term use.

Want to check your whole stack?

The free checker lets you add any combination of supplements and medications at once. Formulate's desktop app goes further — every stack change surfaces interaction alerts automatically.

Medical disclaimer. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.