Mineral
Magnesium Glycinate
Also known as: Chelated magnesium
Highly bioavailable magnesium chelated with glycine. Excellent for sleep, relaxation, and those with sensitive stomachs.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Common questions
How much Magnesium Glycinate should I take?
The typical range is 200-400 mg elemental Mg daily. Safe long-term
When should I take Magnesium Glycinate?
Evening, 1-2h before bed. Optional.
Which form of Magnesium Glycinate is best?
Capsule — Common. Other forms in the catalog: Powder.
Is Magnesium Glycinate safe?
Commonly reported: Very well tolerated. Serious warnings: Caution in kidney disease. Avoid severe kidney disease
Which Magnesium Glycinate supplement scores highest?
Double Wood Magnesium Glycinate Supplement, at 85/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Daily target & upper limit
420 mg / day · UL 350 mgMagnesium Glycinate has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:
Magnesium Glycinate dosage reference →Primary uses
- Sleep support
- Muscle relaxation
- Stress/anxiety
- Magnesium repletion
How it works
- Glycine chelation enhances absorption
- Magnesium regulates GABA
- Glycine independently calming
Dosage
- Typical range
- 200-400 mg elemental Mg daily
- Timing
- Evening, 1-2h before bed
- With food
- Optional
- Duration
- Safe long-term
- Special populations
- Sensitive stomachs
Forms
- Capsule
- Powder
Safety
Common side effects
- Very well tolerated
Contraindications
- Severe kidney failure
Products containing Magnesium Glycinate
Top-scoring supplements in our catalog that list Magnesium Glycinate on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Known interactions
- Cautionwith calcium
High calcium can impair magnesium absorption
- Infowith magnesium
High-dose magnesium may slightly reduce zinc absorption
- Synergywith magnesium
Magnesium needed for vitamin D activation
- Synergywith melatonin
Complementary sleep support
- Synergywith glycine
Both support sleep through different mechanisms
- Cautionwith magnesium
Magnesium may enhance BP lowering effect
Evidence notes
Excellent bioavailability and tolerability
Grade A: Multiple well-designed human trials support the main claims.
Magnesium Glycinate compared head-to-head
Related in Mineral
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.