Mineral
Zinc Picolinate
Also known as: Chelated zinc
A
Evidence
Highly bioavailable zinc for immune function, testosterone, and wound healing. Take with food to avoid nausea.
Primary uses
- Immune support
- Testosterone support
- Wound healing
- Zinc repletion
How it works
- Picolinic acid enhances absorption
- Cofactor for 300+ enzymes
- Required for testosterone synthesis
Dosage
- Typical range
- 15-30 mg daily; up to 50 mg short-term
- Timing
- With food
- With food
- Yes, reduces nausea
- Duration
- Long-term >40mg needs copper
- Special populations
- Athletes, vegetarians, elderly
Forms
- Capsule
- Tablet
- Liquid
Safety
Common side effects
- Nausea without food
- Metallic taste
Contraindications
- None at normal doses
Known interactions
- Warningwith zinc
Zinc depletes copper over time
- Cautionwith zinc
Zinc and iron compete for absorption
- Cautionwith calcium
Calcium may reduce zinc absorption
- Infowith magnesium
High-dose magnesium may slightly reduce zinc absorption
- Synergywith zinc
Quercetin acts as zinc ionophore
- Synergywith zinc
Zinc needed for vitamin A metabolism
Evidence notes
Excellent bioavailability
Grade A: Multiple well-designed human trials support the main claims.
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