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Mineral

Zinc Picolinate

Also known as: Chelated zinc

A
Evidence

Highly bioavailable zinc for immune function, testosterone, and wound healing. Take with food to avoid nausea.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Daily target & upper limit

11 mg / day · UL 40 mg

Zinc Picolinate has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:

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Primary uses

  • Immune support
  • Testosterone support
  • Wound healing
  • Zinc repletion

How it works

  • Picolinic acid enhances absorption
  • Cofactor for 300+ enzymes
  • Required for testosterone synthesis

Dosage

Typical range
15-30 mg daily; up to 50 mg short-term
Timing
With food
With food
Yes, reduces nausea
Duration
Long-term >40mg needs copper
Special populations
Athletes, vegetarians, elderly

Forms

  • Capsule
  • Tablet
  • Liquid

Safety

Common side effects

  • Nausea without food
  • Metallic taste

Contraindications

  • None at normal doses

Known interactions

Evidence notes

Excellent bioavailability

Grade A: Multiple well-designed human trials support the main claims.

Zinc Picolinate compared head-to-head

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.