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copper and zinc

Zinc depletes copper over time

What's happening

Long-term zinc supplementation (>40mg/day) can induce copper deficiency by competing for absorption. This can lead to anemia and neurological issues.

Recommendation

If taking zinc long-term, supplement with copper (ratio of ~15:1 zinc:copper) or take copper separately.

Timing

Take zinc and copper at different times of day (4+ hours apart)

Sources

  • — NIH Office of Dietary Supplements
  • — Journal of Trace Elements

Frequently Asked Questions

Can I take copper and zinc together?

Zinc depletes copper over time. If taking zinc long-term, supplement with copper (ratio of ~15:1 zinc:copper) or take copper separately.

How should I time copper and zinc?

Take zinc and copper at different times of day (4+ hours apart)

Is this interaction dangerous?

This interaction is rated “Warning” by Formulate. Long-term zinc supplementation (>40mg/day) can induce copper deficiency by competing for absorption. This can lead to anemia and neurological issues.

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Medical disclaimer. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.