Primary Research · 2005

Zinc-induced copper deficiency: a report of three cases initially recognized on bone marrow examination

Willis et al. · American Journal of Clinical Nutrition, 2005

Key finding

Documented cases of copper deficiency from chronic high-dose zinc supplementation — supports the 1–2 mg copper pairing guideline.

Read the paper

Open on PubMed

https://pubmed.ncbi.nlm.nih.gov/16155279/

Cited in 1 guide

Guide
Zinc for Immune Support: Timing and Form Matter More Than Dose
Zinc genuinely shortens colds, but only when taken correctly. Lozenges within 24 hours of first symptoms — not pills, not after you're already sick.

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