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Mineral

Copper

Also known as: Copper glycinate, Copper bisglycinate, Copper citrate, Copper gluconate

A
Evidence

Essential trace mineral for iron metabolism, connective tissue, and antioxidant function. Often depleted by high zinc supplementation.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

Add Thorne Copper Bisglycinate to your stack — free
The highest-scored Copper product in our catalog (96/100). Track dose and overlaps in the app.
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Every Copper product we have scored

Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.

Common questions

How much Copper should I take?

The typical range is 1-2mg daily. Safe long-term at appropriate doses

When should I take Copper?

Separate from zinc by several hours. Yes.

Which form of Copper is best?

Copper glycinate — Well-absorbed. Other forms in the catalog: Copper gluconate, Copper citrate, Capsule/tablet.

Is Copper safe?

Commonly reported: Nausea if taken without food, GI upset. Serious warnings: Toxicity possible - don't mega-dose, Wilson's disease contraindication. Wilson's disease - avoid

Which Copper supplement scores highest?

Thorne Copper Bisglycinate, at 96/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.

Daily target & upper limit

0.9 mg / day · UL 10 mg

Copper has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:

Copper dosage reference →

Primary uses

  • Immune cell energy
  • Iron metabolism
  • Antioxidant enzymes
  • Connective tissue
  • Energy production

What systematic reviews concluded

Outcomes that systematic reviews of Copper reached a verdict on: 1 with a benefit, 2 unclear. Each is quoted from a review and linked to it on PubMed. How these were read.

Reviews found a benefit (1)

Benefitemergency contraception effectiveness
“The copper intrauterine device is highly effective and offers long-term contraception for women using it as emergency contraception.” PMID 39701010

Not enough to say: depressive symptoms in coronary artery disease; stuttering severity.

How it works

  • Required for iron absorption and transport
  • Cofactor for lysyl oxidase (collagen)
  • Part of SOD antioxidant
  • Required for energy production

Dosage

Typical range
1-2mg daily
Timing
Separate from zinc by several hours
With food
Yes
Duration
Safe long-term at appropriate doses
Special populations
Those taking zinc, anemia, collagen support

Forms

  • Copper glycinate
  • Copper gluconate
  • Copper citrate
  • Capsule/tablet

Safety

Common side effects

  • Nausea if taken without food
  • GI upset

Contraindications

  • Wilson's disease
  • Copper overload conditions

Products containing Copper

Top-scoring supplements in our catalog that list Copper on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

See all products →

Known interactions

Evidence notes

Essential trace mineral, important to balance with zinc

Grade A: Multiple well-designed human trials support the main claims.

Cited research for Copper

Clinical studies referenced across Formulate guides that mention copper. Each links to the full study page with PubMed source + the guides that cite it.

Related in Mineral

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.