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Thorne SynaQuell +™

SynaQuell +™

88A
Grade A · capsule · 30 servings · $44.00
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Scored by the Formulate Research Team · Last reviewed July 2026

Fish Oil & OmegasBrain HealthCognitionHealthy AgingSleep

Overview: Thorne SynaQuell +™

A multi-ingredient nutritional supplement, formulated to support healthy brain structure and cognitive function* Formulated to support brain health by enhancing cellular energy production and encouraging a healthy balance of inflammatory cytokines.* NSF Certified for Sport®

Score Breakdown

Formulate scores every product across six weighted dimensions. Each dimension is graded independently — hover or tap to see what drove each component.

Evidence Qualityweight 40%
87/ 100
Dose Adequacyweight 35%
86/ 100
Form/Bioavailabilityweight 25%
92/ 100
Transparencyweight 0%
100/ 100
Safety/Redundancyweight 0%
100/ 100
Manufacturing Qualityweight 0%
94/ 100

Ingredients per Serving

IngredientAmount
Betaine AnhydrousTrimethylglycine16 systematic reviews · 88 randomised trials170 mg
Coenzyme Q1081 systematic reviews · 156 randomised trials100 mg
Curcumin PhytosomePhospholipid complex from Sunflower188 systematic reviews · 279 randomised trials500 mg
L-Isoleucine1 systematic review · 6 randomised trials1250 mg
L-Leucine3 systematic reviews · 28 randomised trials2.5 g
MagnesiumMagnesium Bisglycinate250 systematic reviews · 790 randomised trials264 mg
Nicotinamide Riboside5 systematic reviews · 25 randomised trials830 mg
DHADocosahexaenoic Acid4 systematic reviews · 6 randomised trials750 mg
Trans-Resveratrol100 systematic reviews · 156 randomised trials250 mg
RiboflavinRiboflavin 5'-Phosphate Sodium9 systematic reviews · 14 randomised trials200 mg
L-Valine1 systematic review · 7 randomised trials1250 mg
Beta HydroxybutyrateMagnesium Beta Hydroxybutyrate8 systematic reviews · 91 randomised trials1500 mg
Magnesium Beta Hydroxybutyrate8 systematic reviews · 91 randomised trials176 mg
GlutathioneReduced132 systematic reviews · 768 randomised trials1000 mg

Certifications & Testing

NSF Certified for SportGluten FreeDairy FreeSoy FreeThorne VerifiedNatural FlavorsNatural ColorsGMP Certified

Other Ingredients

Carboxymethylcellulose Gum, Citric Acid, Flavors, Rebaudioside A

Recommended Use

Mix 1 scoop with at least 12 ounces of water two times daily or as recommended by your health-care practitioner.

Warnings

CALIFORNIA WARNING Risk of reproductive harm from exposure to lead. See www.P65Warnings.ca.gov/food. ALLERGY WARNING This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PREGNANCY WARNING If pregnant or nursing, do not use this product. INTERACTIONS Curcumin has been shown to reduce the therapeutic efficacy of cyclophosphamide (Cytoxan) in

Frequently Asked Questions

What is Thorne SynaQuell +™'s Formulate score?

Thorne SynaQuell +™ scores 88 out of 100 (grade A) on Formulate's ingredient-level rubric, which weighs evidence quality, dose accuracy, bioavailability, transparency, safety, and manufacturing practices.

Is Thorne SynaQuell +™ worth it?

Thorne SynaQuell +™ scores 88/100 (grade A). That puts it in Formulate's top tier: its ingredient doses, forms, and label transparency hold up against the clinical evidence, and it carries credible third-party testing. Formulate grades every product with the same automated rubric, so the score reflects the formula — not marketing or sponsorships.

What's in Thorne SynaQuell +™?

Each serving contains Betaine Anhydrous (170 mg), Coenzyme Q10 (100 mg), Curcumin Phytosome (500 mg), L-Isoleucine (1250 mg), and more. Serving size: 1 Scoop. 30 servings per container.

How do I take synaquell +™?

Mix 1 scoop with at least 12 ounces of water two times daily or as recommended by your health-care practitioner.

Who makes SynaQuell +™?

SynaQuell +™ is made by Thorne. See Formulate's full grade and product lineup for Thorne on its brand page.

Is Thorne SynaQuell +™ third-party tested?

Thorne lists the following certifications and testing for this product: NSF Certified for Sport, Gluten Free, Dairy Free, Soy Free, Thorne Verified, Natural Flavors, Natural Colors, GMP Certified.

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Disclosure. Formulate may earn a commission from purchases made through links on this page. Commissions never influence scores — every product is graded by the same automated rubric. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.