SynaQuell +™
Scored by the Formulate Research Team · Last reviewed May 2026
Overview: Thorne SynaQuell +™
A multi-ingredient nutritional supplement, formulated to support healthy brain structure and cognitive function* Formulated to support brain health by enhancing cellular energy production and encouraging a healthy balance of inflammatory cytokines.* NSF Certified for Sport®
Score Breakdown
Formulate scores every product across six weighted dimensions. Each dimension is graded independently — hover or tap to see what drove each component.
Ingredients per Serving
| Ingredient | Amount |
|---|---|
| Betaine AnhydrousTrimethylglycine | 170 mg |
| Coenzyme Q10 | 100 mg |
| Curcumin PhytosomePhospholipid complex from Sunflower | 500 mg |
| L-Isoleucine | 1250 mg |
| L-Leucine | 2.5 g |
| MagnesiumMagnesium Bisglycinate | 264 mg |
| Nicotinamide Riboside | 830 mg |
| DHADocosahexaenoic Acid | 750 mg |
| Trans-Resveratrol | 250 mg |
| RiboflavinRiboflavin 5'-Phosphate Sodium | 200 mg |
| L-Valine | 1250 mg |
| Beta HydroxybutyrateMagnesium Beta Hydroxybutyrate | 1500 mg |
| Magnesium Beta Hydroxybutyrate | 176 mg |
| GlutathioneReduced | 1000 mg |
Certifications & Testing
Other Ingredients
Carboxymethylcellulose Gum, Citric Acid, Flavors, Rebaudioside A
Recommended Use
Mix 1 scoop with at least 12 ounces of water two times daily or as recommended by your health-care practitioner.
Warnings
CALIFORNIA WARNING Risk of reproductive harm from exposure to lead. See www.P65Warnings.ca.gov/food. ALLERGY WARNING This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PREGNANCY WARNING If pregnant or nursing, do not use this product. INTERACTIONS Curcumin has been shown to reduce the therapeutic efficacy of cyclophosphamide (Cytoxan) in
Frequently Asked Questions
What is Thorne SynaQuell +™'s Formulate score?
Thorne SynaQuell +™ scores 90 out of 100 (grade A) on Formulate's ingredient-level rubric, which weighs evidence quality, dose accuracy, bioavailability, transparency, safety, and manufacturing practices.
Is Thorne SynaQuell +™ worth it?
Thorne SynaQuell +™ scores 90/100 (grade A). That puts it in Formulate's top tier: its ingredient doses, forms, and label transparency hold up against the clinical evidence, and it carries credible third-party testing. Formulate grades every product with the same automated rubric, so the score reflects the formula — not marketing or sponsorships.
What's in Thorne SynaQuell +™?
Each serving contains Betaine Anhydrous (170 mg), Coenzyme Q10 (100 mg), Curcumin Phytosome (500 mg), L-Isoleucine (1250 mg), and more. Serving size: 1 Scoop. 30 servings per container.
How do I take synaquell +™?
Mix 1 scoop with at least 12 ounces of water two times daily or as recommended by your health-care practitioner.
Who makes SynaQuell +™?
SynaQuell +™ is made by Thorne. See Formulate's full grade and product lineup for Thorne on its brand page.
Is Thorne SynaQuell +™ third-party tested?
Thorne lists the following certifications and testing for this product: NSF Certified for Sport, Gluten Free, Dairy Free, Soy Free, Thorne Verified, Natural Flavors, Natural Colors, GMP Certified.
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Disclosure. Formulate may earn a commission from purchases made through links on this page. Commissions never influence scores — every product is graded by the same automated rubric. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.