Skip to main content

Antioxidant

Meriva® Curcumin Phytosome® (Curcuma longa)

Also known as: Meriva, Curcumin Phytosome, Curcumin-phospholipid complex, Curcuma longa extract

B
Evidence

Meriva® is a patented phytosome complex of curcumin bound to phospholipids, designed to improve absorption and bioavailability compared to standard curcumin. Clinical evidence supports its use for inflammatory support and cognitive health, with superior pharmacokinetics compared to unformulated curcumin.

Primary uses

  • Inflammatory response support
  • Cognitive and brain health
  • Antioxidant protection
  • Joint comfort

How it works

  • NF-κB pathway inhibition
  • Free radical scavenging via polyphenol activity
  • Phospholipid complex enhances intestinal absorption and lymphatic uptake
  • Modulation of pro-inflammatory cytokines

Dosage

Typical range
500–1000 mg daily (providing 90–180 mg curcuminoids at 18% standardization)
Timing
With meals for optimal absorption
With food
Recommended; fat-soluble and absorption enhanced with dietary fat
Duration
Minimum 4–8 weeks for inflammatory support; long-term safety supported in clinical trials up to 12 months
Special populations
Generally well-tolerated; pregnant/nursing should consult healthcare provider; may interact with anticoagulants at very high doses

Forms

  • Capsule· 70/100
  • Powder· 70/100

Safety

Common side effects

  • Mild gastrointestinal upset (rare with Meriva due to improved tolerability)
  • Headache (uncommon)
  • Diarrhea (infrequent at typical doses)

Contraindications

  • Active bleeding disorders without medical supervision
  • Scheduled surgery (discontinue 1–2 weeks prior)
  • High-dose warfarin or antiplatelet therapy (consult healthcare provider)
  • Biliary obstruction or severe liver disease

Evidence notes

Multiple human clinical trials demonstrate Meriva's efficacy for joint comfort and inflammatory markers with superior bioavailability vs. standard curcumin. Evidence is good but not as extensive as basic curcumin; phytosome technology is well-documented but specific applications remain moderately studied.

Grade B: Some human trials support key claims; further confirmation needed.

Related in Antioxidant

Check a full stack

Formulate's free interaction checker lets you paste in any combination of supplements and medications at once — every pairing flags severity, timing, and cited evidence.

Open the checker

Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.