Antioxidant
Luteolin
Also known as: Luteolin flavonoid
Flavonoid with potent anti-inflammatory and neuroprotective properties. Inhibits mast cells and supports brain health.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Luteolin product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Thorne Advanced Testosterone Support | 88 A | $1.43 |
| 2 | Pure Encapsulations Brain Reset | 88 A | $1.32 |
| 3 | Pure Encapsulations Hist Reset | 84 A- | $1.02 |
| 4 | Pure Encapsulations LVR Formula | 81 A- | $0.73 |
| 5 | Pure Encapsulations Ultra B-Complex with PQQ | 81 A- | $1.51 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Luteolin should I take?
The typical range is 100-400mg daily. Safe long-term
When should I take Luteolin?
With meals. Yes.
Which form of Luteolin is best?
Capsule — Standard. Other forms in the catalog: Liposomal.
Is Luteolin safe?
Commonly reported: Well tolerated, Mild GI. Serious warnings: None significant. Safe
Which Luteolin supplement scores highest?
Thorne Advanced Testosterone Support, at 88/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Neuroprotection
- Anti-inflammatory
- Mast cell stabilization
- Brain fog
What systematic reviews concluded
Outcomes that systematic reviews of Luteolin reached a verdict on: 1 unclear. Each is quoted from a review and linked to it on PubMed. How these were read.
Not enough to say: diabetes and its complications.
1 finding from reviews in specific patient groups (such as cancer, pregnancy or surgery) is not shown here.
How it works
- Inhibits mast cell activation
- Crosses blood-brain barrier
- NF-kB inhibition
- Microglial modulation
Dosage
- Typical range
- 100-400mg daily
- Timing
- With meals
- With food
- Yes
- Duration
- Safe long-term
- Special populations
- Brain fog, mast cell issues, neuroinflammation
Forms
- Capsule
- Liposomal
Safety
Common side effects
- Well tolerated
- Mild GI
Contraindications
- Pregnancy
Products containing Luteolin
Top-scoring supplements in our catalog that list Luteolin on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Research supports anti-inflammatory and neuroprotective effects
Grade B: Some human trials support key claims; further confirmation needed.
Related in Antioxidant
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.