Antioxidant
Curcumin 95%
Also known as: Curcumin, Diferuloylmethane, Turmeric Extract, Standardized Curcumin
Curcumin is the primary active polyphenol compound from turmeric with demonstrated anti-inflammatory and antioxidant properties. Standardized extracts (95%+) provide concentrated doses with improved bioavailability compared to whole turmeric powder.
Primary uses
- Anti-inflammatory support
- Antioxidant protection
- Joint health and mobility
- Cognitive function support
- General inflammation management
- Joint health
- Cognitive support
- General wellness
How it works
- NF-κB pathway inhibition
- Free radical scavenging
- COX-2 and 5-LOX inhibition
- Nrf2 activation
Dosage
- Typical range
- 400-1200 mg daily (standardized to 95% curcuminoids)
- Timing
- With meals (preferably with fat sources)
- With food
- Highly recommended; fat and piperine significantly enhance absorption
- Duration
- Safe for long-term use; effects may take 4-8 weeks to manifest
- Special populations
- Pregnancy/nursing: consult healthcare provider; may have anti-platelet effects at high doses
Forms
- Powder· 70/100
- Capsule· 70/100
- Softgel· 70/100
- Liquid extract· 70/100
- Extract· 70/100
Safety
Common side effects
- Mild gastrointestinal upset
- Nausea (at high doses)
- Headache (rare)
Contraindications
- Biliary obstruction or gallstones
- Concurrent anticoagulant therapy (potential additive effect)
- Bleeding disorders
- Pregnancy (high doses)
Evidence notes
Good clinical evidence for anti-inflammatory and antioxidant effects; multiple RCTs support joint health and cognitive benefits. Evidence is strongest when combined with bioavailability enhancers like piperine.
Grade B: Some human trials support key claims; further confirmation needed.
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