Antioxidant
Citrus Bioflavonoids
Also known as: Bioflavonoids, Hesperidin, Rutin, Quercetin
Plant compounds from citrus fruits that enhance vitamin C absorption and provide antioxidant, anti-inflammatory, and vascular support benefits.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Vitamin C enhancement
- Vascular health
- Capillary strength
- Antioxidant support
How it works
- Enhance vitamin C absorption and retention
- Strengthen capillary walls
- Antioxidant and anti-inflammatory effects
- Support collagen synthesis
Dosage
- Typical range
- 250-1000 mg daily
- Timing
- With vitamin C
- With food
- Optional
- Duration
- Safe long-term
- Special populations
- Those taking vitamin C supplements
Forms
- Complex/blend
- Hesperidin
- Rutin
Safety
Common side effects
- Generally well tolerated
Contraindications
- None known
Products containing Citrus Bioflavonoids
Top-scoring supplements in our catalog that list Citrus Bioflavonoids on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.




Evidence notes
Synergistic with vitamin C; moderate evidence for vascular health
Grade B: Some human trials support key claims; further confirmation needed.
Cited research for Citrus Bioflavonoids
Clinical studies referenced across Formulate guides that mention citrus bioflavonoids. Each links to the full study page with PubMed source + the guides that cite it.
Related in Antioxidant
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.