Antioxidant
Citrus Bioflavonoids Complex
Also known as: citrus flavonoids, citrus extract, hesperidin complex
A mixture of plant compounds from citrus fruits including hesperidin, diosmin, and naringin that act as antioxidants and may support vascular health. Commonly used to enhance vitamin C absorption and support capillary integrity.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Antioxidant support
- Vascular health
- Vitamin C synergy
- Capillary integrity
How it works
- Free radical scavenging
- Collagen cross-linking support
- Vascular endothelial support
Dosage
- Typical range
- 500–2000 mg daily
- Timing
- With meals for optimal absorption
- With food
- Recommended; taken with vitamin C enhances effect
- Duration
- Safe for long-term use
- Special populations
- No known contraindications in healthy populations
Forms
- powder· 70/100
- capsule· 70/100
- extract· 70/100
Safety
Common side effects
- Generally well-tolerated; rare mild GI upset at high doses
Products containing Citrus Bioflavonoids Complex
Top-scoring supplements in our catalog that list Citrus Bioflavonoids Complex on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
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Evidence notes
Moderate evidence for vascular support and antioxidant benefits, particularly hesperidin. Most research on isolated bioflavonoids rather than complex mixtures.
Grade B: Some human trials support key claims; further confirmation needed.
Related in Antioxidant
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.