Antioxidant

Sorghum bicolor Extract (Leaf) with Polyphenols

Also known as: ReDaxin™, Red Sorghum Bioflavonoid Complex, Sorghum leaf extract, Red sorghum extract

Evidence

ReDaxin™ is a standardized sorghum leaf extract rich in polyphenols and bioflavonoids traditionally used in Asian cuisines for potential antioxidant and metabolic support. Limited clinical research exists on this specific extract in humans, though sorghum is recognized as a polyphenol-rich grain with antioxidant properties.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

Antioxidant support
Metabolic health
General wellness

How it works

Polyphenol-mediated free radical scavenging
Potential modulation of antioxidant enzyme systems
Anti-inflammatory signaling through flavonoid pathways

Dosage

Typical range: 300–600 mg daily (standardized to 20% polyphenols)
Timing: With meals for optimal absorption
With food: Recommended; polyphenols absorb better with dietary fat
Duration: Typical use as a daily antioxidant supplement; long-term safety data is limited
Special populations: Pregnant/nursing women should consult healthcare provider; safety in children not established

Forms

Capsule· 70/100
Powder· 70/100

Safety

Common side effects

Generally well-tolerated; mild gastrointestinal effects possible at high doses

Contraindications

Known sorghum allergy or grass pollen sensitivity
Use with caution in individuals with polyphenol-sensitive conditions

Evidence notes

While sorghum is recognized as a polyphenol-rich food source with in vitro antioxidant capacity, clinical human trials specifically evaluating ReDaxin™ or sorghum leaf extract at standardized doses are limited. Evidence relies primarily on in vitro studies, traditional use, and general polyphenol biology rather than robust RCT data.

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.