Antioxidant
Sesamum indicum Extract (Sesame Seed Extract, 70% Sesamins)
Also known as: sesame seed extract, sesamin, sesamol, Sesamum indicum
Sesame seed extract standardized to 70% sesamins is a plant lignan concentrate with preliminary evidence for antioxidant and anti-inflammatory properties. Most human evidence remains limited, with potential benefits primarily demonstrated in animal models and small clinical studies.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Sesamum indicum Extract (Sesame Seed Extract, 70% Sesamins) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Life Extension Super Omega-3 Plus | 75 B+ | $0.66 |
| 2 | Life Extension Super Omega-3 | 71 B | $0.46 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Sesamum indicum Extract (Sesame Seed Extract, 70% Sesamins) should I take?
The typical range is 50-200 mg daily (based on sesamin content). Typically used continuously; effects may require 4-8 weeks of consistent use
When should I take Sesamum indicum Extract (Sesame Seed Extract, 70% Sesamins)?
With meals for optimal absorption. Recommended; sesamins are fat-soluble compounds.
Which form of Sesamum indicum Extract (Sesame Seed Extract, 70% Sesamins) is best?
Capsule. Other forms in the catalog: Powder, Extract.
Is Sesamum indicum Extract (Sesame Seed Extract, 70% Sesamins) safe?
Commonly reported: Generally well-tolerated at typical doses, Rare: mild gastrointestinal upset, Rare: allergic reactions in sesame-sensitive individuals.
Which Sesamum indicum Extract (Sesame Seed Extract, 70% Sesamins) supplement scores highest?
Life Extension Super Omega-3 Plus, at 75/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Antioxidant support
- Anti-inflammatory support
- Cardiovascular health
- Lipid metabolism support
How it works
- Potent antioxidant activity via free radical scavenging
- Inhibition of lipid peroxidation
- Modulation of inflammatory cytokines
- Potential enhancement of antioxidant enzyme activity (SOD, catalase)
Dosage
- Typical range
- 50-200 mg daily (based on sesamin content)
- Timing
- With meals for optimal absorption
- With food
- Recommended; sesamins are fat-soluble compounds
- Duration
- Typically used continuously; effects may require 4-8 weeks of consistent use
- Special populations
- Pregnant/nursing women should consult healthcare provider; limited safety data in these populations
Forms
- Capsule· 70/100
- Powder· 70/100
- Extract· 70/100
Safety
Common side effects
- Generally well-tolerated at typical doses
- Rare: mild gastrointestinal upset
- Rare: allergic reactions in sesame-sensitive individuals
Contraindications
- Sesame allergy or sensitization
- Use with caution in patients with bleeding disorders (theoretical risk based on animal data)
Products containing Sesamum indicum Extract (Sesame Seed Extract, 70% Sesamins)
Top-scoring supplements in our catalog that list Sesamum indicum Extract (Sesame Seed Extract, 70% Sesamins) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Sesamins have substantial in vitro and animal model evidence for antioxidant and anti-inflammatory effects. Human clinical trials are limited in number and sample size; most available studies involve small cohorts or focus on sesame oil rather than standardized lignan extracts. Grade C reflects preliminary but promising evidence lacking robust large-scale RCT confirmation.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.