Antioxidant
Hesperidin
Also known as: Citrus bioflavonoid, Hesperidin chalcone
Citrus flavonoid supporting vascular health and circulation. Reduces capillary permeability and supports venous tone.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Hesperidin product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Pure Encapsulations Daily Immune | 83 A- | $1.13 |
| 2 | Pure Encapsulations Aller-Essentials | 81 A- | $1.11 |
| 3 | NOW Foods Clinical Strength Ocu Support | 81 A- | $0.73 |
| 4 | Integrative Therapeutics Vitamin C With Quercetin | 80 A- | $0.47 |
| 5 | Solgar Formula VM-75 | 80 A- | $0.24 |
| 6 | Solgar Formula VM-75 Iron-Free | 80 A- | $0.23 |
| 7 | Pure Encapsulations Acerola/Flavonoid | 79 B+ | $0.93 |
| 8 | Life Extension AMPK Metabolic Activator | 79 B+ | $0.95 |
| 9 | Solgar Ester-C Plus Vitamin C | 79 B+ | $0.16 |
| 10 | Vital Nutrients Vitamin C with Bioflavonoids | 79 B+ | $0.50 |
| 11 | Solgar Quercetin Complex with Ester-C Plus | 78 B+ | $0.23 |
| 12 | Country Life Chewable Vitamin C 500 mg | 78 B+ | $0.24 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Hesperidin should I take?
The typical range is 250-500mg daily. Safe long-term
When should I take Hesperidin?
With meals. Yes.
Which form of Hesperidin is best?
Capsule — Standard. Other forms in the catalog: Micronized.
Is Hesperidin safe?
Commonly reported: Well tolerated, Rare GI upset. Serious warnings: None significant. Safe
Which Hesperidin supplement scores highest?
Pure Encapsulations Daily Immune, at 83/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Vascular health
- Circulation
- Capillary strength
- Hemorrhoid support
How it works
- Strengthens capillaries
- Reduces venous permeability
- Anti-inflammatory
- Enhances vitamin C function
Dosage
- Typical range
- 250-500mg daily
- Timing
- With meals
- With food
- Yes
- Duration
- Safe long-term
- Special populations
- Vascular issues, hemorrhoids, bruising
Forms
- Capsule
- Micronized
Safety
Common side effects
- Well tolerated
- Rare GI upset
Contraindications
- None known
Products containing Hesperidin
Top-scoring supplements in our catalog that list Hesperidin on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Well-studied for vascular and circulation benefits
Grade B: Some human trials support key claims; further confirmation needed.
Related in Antioxidant
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.