Vitamin
Vitamin B2 (Riboflavin)
Also known as: Riboflavin, Riboflavin-5-phosphate, R5P, B2
Essential B vitamin involved in energy production, antioxidant function, and metabolism of other B vitamins. The active form (R5P) is preferred.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Vitamin B2 (Riboflavin) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Thorne Craving and Stress Support | 93 A | $1.33 |
| 2 | Thorne Methyl-Guard Plus | 91 A | $2.07 |
| 3 | Pure Encapsulations B-Complex liquid | 91 A | $1.34 |
| 4 | Nature Made B-Complex with C Caplets | 90 A | $0.11 |
| 5 | Nutricost Pre-Workout For Women Powder | 89 A | $0.73 |
| 6 | Nutricost Pre-Workout Complex | 89 A | $0.83 |
| 7 | Garden of Life Vitamin Code Raw B-Complex | 89 A | $0.50 |
| 8 | Life Extension Boron | 89 A | $0.06 |
| 9 | Thorne Advanced Nutrients | 88 A | $2.40 |
| 10 | Thorne Basic Nutrients 2/Day | 88 A | $0.60 |
| 11 | Thorne Basic Prenatal | 88 A | $1.23 |
| 12 | Thorne Men's Multi 50+ | 88 A | $1.87 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Vitamin B2 (Riboflavin) should I take?
The typical range is 10-400 mg daily (400mg for migraines). Safe for long-term use
When should I take Vitamin B2 (Riboflavin)?
With food. Yes, improves absorption.
Which form of Vitamin B2 (Riboflavin) is best?
Riboflavin-5-phosphate (R5P) — Active form, best choice. Other forms in the catalog: Riboflavin.
Is Vitamin B2 (Riboflavin) safe?
Commonly reported: Bright yellow urine (harmless), Very well tolerated. Serious warnings: None. Safe
Which Vitamin B2 (Riboflavin) supplement scores highest?
Thorne Craving and Stress Support, at 93/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Daily target & upper limit
1.3 mg / dayVitamin B2 (Riboflavin) has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:
Vitamin B2 (Riboflavin) dosage reference →Primary uses
- Energy production
- Migraine prevention
- Antioxidant support
- B-vitamin metabolism
How it works
- Precursor to FAD and FMN coenzymes
- Required for electron transport chain
- Regenerates glutathione (antioxidant)
- Required for folate and B6 activation
Dosage
- Typical range
- 10-400 mg daily (400mg for migraines)
- Timing
- With food
- With food
- Yes, improves absorption
- Duration
- Safe for long-term use
- Special populations
- Migraine sufferers may need higher doses
Forms
- Riboflavin-5-phosphate (R5P)
- Riboflavin
Safety
Common side effects
- Bright yellow urine (harmless)
- Very well tolerated
Contraindications
- None known
Products containing Vitamin B2 (Riboflavin)
Top-scoring supplements in our catalog that list Vitamin B2 (Riboflavin) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Well-established essential nutrient, good evidence for migraine prevention
Grade A: Multiple well-designed human trials support the main claims.
Related in Vitamin
Check a full stack
Formulate's free interaction checker lets you paste in any combination of supplements and medications at once — every pairing flags severity, timing, and cited evidence.
Open the checkerWhere does Vitamin B2 (Riboflavin) fit in your stack?
Answer two questions and get a stack graded on research — every ingredient scored on the evidence behind it, not the marketing.
Build my stack2 questions · free · no account needed to start
Also on iPhone — get the free app
Evidence-based supplement guides, no spam
We send a short digest when new guides drop — nothing else. No affiliate pushes, no sponsored content, unsubscribe anytime.
Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.