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Vitamin

Pantothenic Acid (Calcium Pantothenate)

Also known as: vitamin B5, pantothenate, calcium pantothenate, pantothenic acid

A
Evidence

A B-complex vitamin required for the synthesis of coenzyme A, which is critical for energy metabolism and synthesis of hormones, cholesterol, and amino acids. Calcium pantothenate is the stable supplemental form.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Daily target & upper limit

5 mg / day

Pantothenic Acid (Calcium Pantothenate) has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:

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Primary uses

  • Energy production
  • Hormone synthesis
  • Stress response support
  • Wound healing
  • Pantothenic acid deficiency prevention

How it works

  • Precursor for coenzyme A (CoA) synthesis
  • Essential for fatty acid oxidation
  • Supports steroid hormone synthesis
  • Involved in acetylation reactions

Dosage

Typical range
5 mg daily (adequate intake); 5-100 mg daily for supplementation
Timing
With or without food
With food
No specific requirement
Duration
Safe for long-term use; water-soluble excess is excreted
Special populations
Athletes may benefit from higher intakes; bioavailability is high from supplemental forms

Forms

  • calcium pantothenate· 70/100
  • pantothenic acid· 70/100

Safety

Common side effects

  • Extremely rare at supplemental doses
  • Diarrhea may occur at very high doses (>10 g daily)

Contraindications

  • Hypersensitivity to pantothenic acid or calcium

Products containing Pantothenic Acid (Calcium Pantothenate)

Top-scoring supplements in our catalog that list Pantothenic Acid (Calcium Pantothenate) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

Complement
Gut Nurture
89
Thorne
Advanced Nutrients
88
Thorne
Basic Nutrients 2/Day
88
Thorne
Basic Prenatal
88
See all products →

Evidence notes

Strong evidence for deficiency prevention and essential metabolic functions. RCT evidence supports efficacy in normal supplemental ranges. Well-established biochemical role.

Grade A: Multiple well-designed human trials support the main claims.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.