Vitamin
Pantothenic Acid (Calcium Pantothenate)
Also known as: vitamin B5, pantothenate, calcium pantothenate, pantothenic acid
A B-complex vitamin required for the synthesis of coenzyme A, which is critical for energy metabolism and synthesis of hormones, cholesterol, and amino acids. Calcium pantothenate is the stable supplemental form.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Pantothenic Acid (Calcium Pantothenate) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Pure Encapsulations B-Complex liquid | 91 A | $1.34 |
| 2 | Nature Made B-Complex with C Caplets | 90 A | $0.11 |
| 3 | Complement Gut Nurture | 89 A | $1.93 |
| 4 | Pure Encapsulations Pantothenic Acid | 89 A | $0.22 |
| 5 | Garden of Life Vitamin Code Raw B-Complex | 89 A | $0.50 |
| 6 | MegaFood Skin, Nails & Hair 2 | 89 A | $0.87 |
| 7 | Thorne Advanced Nutrients | 88 A | $2.40 |
| 8 | Thorne Basic Nutrients 2/Day | 88 A | $0.60 |
| 9 | Thorne Basic Prenatal | 88 A | $1.23 |
| 10 | Thorne Men's Multi 50+ | 88 A | $1.87 |
| 11 | BulkSupplements Vitamin B5 Capsules | 88 A | $0.03 |
| 12 | Thorne Emotion Balance Support | 87 A | $1.05 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Pantothenic Acid (Calcium Pantothenate) should I take?
The typical range is 5 mg daily (adequate intake); 5-100 mg daily for supplementation. Safe for long-term use; water-soluble excess is excreted
When should I take Pantothenic Acid (Calcium Pantothenate)?
With or without food. No specific requirement.
Which form of Pantothenic Acid (Calcium Pantothenate) is best?
calcium pantothenate. Other forms in the catalog: pantothenic acid.
Is Pantothenic Acid (Calcium Pantothenate) safe?
Commonly reported: Extremely rare at supplemental doses, Diarrhea may occur at very high doses (>10 g daily).
Which Pantothenic Acid (Calcium Pantothenate) supplement scores highest?
Pure Encapsulations B-Complex liquid, at 91/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Daily target & upper limit
5 mg / dayPantothenic Acid (Calcium Pantothenate) has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:
Pantothenic Acid (Calcium Pantothenate) dosage reference →Primary uses
- Energy production
- Hormone synthesis
- Stress response support
- Wound healing
- Pantothenic acid deficiency prevention
How it works
- Precursor for coenzyme A (CoA) synthesis
- Essential for fatty acid oxidation
- Supports steroid hormone synthesis
- Involved in acetylation reactions
Dosage
- Typical range
- 5 mg daily (adequate intake); 5-100 mg daily for supplementation
- Timing
- With or without food
- With food
- No specific requirement
- Duration
- Safe for long-term use; water-soluble excess is excreted
- Special populations
- Athletes may benefit from higher intakes; bioavailability is high from supplemental forms
Forms
- calcium pantothenate· 70/100
- pantothenic acid· 70/100
Safety
Common side effects
- Extremely rare at supplemental doses
- Diarrhea may occur at very high doses (>10 g daily)
Contraindications
- Hypersensitivity to pantothenic acid or calcium
Products containing Pantothenic Acid (Calcium Pantothenate)
Top-scoring supplements in our catalog that list Pantothenic Acid (Calcium Pantothenate) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Strong evidence for deficiency prevention and essential metabolic functions. RCT evidence supports efficacy in normal supplemental ranges. Well-established biochemical role.
Grade A: Multiple well-designed human trials support the main claims.
Related in Vitamin
Check a full stack
Formulate's free interaction checker lets you paste in any combination of supplements and medications at once — every pairing flags severity, timing, and cited evidence.
Open the checkerWhere does Pantothenic Acid (Calcium Pantothenate) fit in your stack?
Answer two questions and get a stack graded on research — every ingredient scored on the evidence behind it, not the marketing.
Build my stack2 questions · free · no account needed to start
Also on iPhone — get the free app
Evidence-based supplement guides, no spam
We send a short digest when new guides drop — nothing else. No affiliate pushes, no sponsored content, unsubscribe anytime.
Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.