Vitamin

Pantothenic Acid (Vitamin B5)

Also known as: Vitamin B5, Calcium pantothenate, Pantethine, Pantothenic Acid (B5 for Adrenals)

Evidence

Essential for adrenal hormone synthesis. Supports cortisol production capacity.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

Find the best Pantothenic Acid (Vitamin B5) supplements — free

See Pantothenic Acid (Vitamin B5) products scored on dose & form, then track your intake in the app.

Open app →

Daily target & upper limit

5 mg / day

Pantothenic Acid (Vitamin B5) has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:

Pantothenic Acid (Vitamin B5) dosage reference →

Primary uses

Adrenal support
Energy metabolism
Hormone synthesis
Adrenal hormone synthesis
Stress support

How it works

Precursor to Coenzyme A
Essential for steroid hormone synthesis
Energy metabolism

Dosage

Typical range: 100-500mg daily
Timing: With meals
With food: Yes
Duration: Daily B vitamin
Special populations: Adrenal support, high stress

Forms

Calcium pantothenate
Pantethine
B-complex

Safety

Common side effects

Generally very well tolerated
Diarrhea at high doses

Contraindications

None

Products containing Pantothenic Acid (Vitamin B5)

Top-scoring supplements in our catalog that list Pantothenic Acid (Vitamin B5) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

Basic Nutrients 2/Day

Thorne

Basic Prenatal

See all products →

Evidence notes

Essential for adrenal function

Grade B: Some human trials support key claims; further confirmation needed.

Related in Vitamin

Check a full stack

Formulate's free interaction checker lets you paste in any combination of supplements and medications at once — every pairing flags severity, timing, and cited evidence.

Open the checker

Where does Pantothenic Acid (Vitamin B5) fit in your stack?

Answer two questions and get a stack graded on research — every ingredient scored on the evidence behind it, not the marketing.

Build my stack

2 questions · free · no account needed to start

Also on iPhone — get the free app

📬 Get new guides in your inbox

Evidence-based supplement guides, no spam

We send a short digest when new guides drop — nothing else. No affiliate pushes, no sponsored content, unsubscribe anytime.

Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.