Longevity
NR (Nicotinamide Riboside)
Also known as: Nicotinamide riboside, Niagen, NR chloride
B
Evidence
NAD+ precursor with extensive human safety data. First NAD+ precursor with significant clinical trials. Patented as Niagen.
Primary uses
- NAD+ support
- Cellular energy
- Longevity
- Healthy aging
How it works
- Converted to NMN then NAD+
- Supports sirtuin activity
- Mitochondrial function
- Cellular repair pathways
Dosage
- Typical range
- 250-500mg daily
- Timing
- Morning
- With food
- Can be taken with or without
- Duration
- Established safety profile
- Special populations
- Longevity, energy, healthy aging
Forms
- Capsule
Safety
Common side effects
- Well tolerated
- Nausea rare
- Flushing rare
Contraindications
- None established
Evidence notes
Good human trial data, established safety profile
Grade B: Some human trials support key claims; further confirmation needed.
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