Longevity
NR (Nicotinamide Riboside)
Also known as: Nicotinamide riboside, Niagen, NR chloride
NAD+ precursor with extensive human safety data. First NAD+ precursor with significant clinical trials. Patented as Niagen.
Primary uses
- NAD+ support
- Cellular energy
- Longevity
- Healthy aging
How it works
- Converted to NMN then NAD+
- Supports sirtuin activity
- Mitochondrial function
- Cellular repair pathways
Dosage
- Typical range
- 250-500mg daily
- Timing
- Morning
- With food
- Can be taken with or without
- Duration
- Established safety profile
- Special populations
- Longevity, energy, healthy aging
Forms
- Capsule
Safety
Common side effects
- Well tolerated
- Nausea rare
- Flushing rare
Contraindications
- None established
Products containing NR (Nicotinamide Riboside)
Top-scoring supplements in our catalog that list NR (Nicotinamide Riboside) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
See all products →Evidence notes
Good human trial data, established safety profile
Grade B: Some human trials support key claims; further confirmation needed.
Related in Longevity
Check a full stack
Formulate's free interaction checker lets you paste in any combination of supplements and medications at once — every pairing flags severity, timing, and cited evidence.
Open the checkerMedical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.



