Longevity
Nicotinamide Riboside (NR)
Also known as: NR, Niagen, TruNiagen
NAD+ precursor supporting cellular energy and longevity. May enhance neuroplasticity and mitochondrial function.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Nicotinamide Riboside (NR) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Life Extension NAD+ Cell Regenerator | 91 A | $0.60 |
| 2 | Thorne Advanced Nutrients | 88 A | $2.40 |
| 3 | Thorne SynaQuell +™ | 88 A | $1.47 |
| 4 | Pure Encapsulations NR Longevity | 87 A | $2.17 |
| 5 | Thorne Brain Factors | 84 A- | $1.70 |
| 6 | Thorne ResveraCel | 84 A- | $2.00 |
| 7 | Life Extension NAD+ Cell Regenerator and Resveratrol Elite | 84 A- | $1.50 |
| 8 | Thorne NiaCel® 400 | 81 A- | $1.23 |
| 9 | Thorne Daily Greens Plus | 79 B+ | $0.83 |
| 10 | Codeage Liposomal Nicotinamide Riboside+ Large | 78 B+ | $1.00 |
| 11 | Thorne Collagen Plus | 74 B+ | $2.23 |
| 12 | Thorne Collagen Fit | 73 B+ | $1.87 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Nicotinamide Riboside (NR) should I take?
The typical range is 250-500 mg daily. Long-term benefits
When should I take Nicotinamide Riboside (NR)?
Morning. Optional.
Which form of Nicotinamide Riboside (NR) is best?
Capsules — Niagen common brand.
Is Nicotinamide Riboside (NR) safe?
Commonly reported: Mild nausea, Flushing rare. Serious warnings: None established. Safe
Which Nicotinamide Riboside (NR) supplement scores highest?
Life Extension NAD+ Cell Regenerator, at 91/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- NAD+ support
- Longevity
- Cellular energy
- Neuroprotection
How it works
- Converted to NAD+ efficiently
- Supports sirtuin activity
- Mitochondrial biogenesis
Dosage
- Typical range
- 250-500 mg daily
- Timing
- Morning
- With food
- Optional
- Duration
- Long-term benefits
- Special populations
- Aging, energy concerns
Forms
- Capsules
Safety
Common side effects
- Mild nausea
- Flushing rare
Contraindications
- None known
Products containing Nicotinamide Riboside (NR)
Top-scoring supplements in our catalog that list Nicotinamide Riboside (NR) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
NAD+ precursor with longevity interest
Grade B: Some human trials support key claims; further confirmation needed.
Related in Longevity
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.