Longevity

PQQ (Pyrroloquinoline Quinone)

Also known as: PQQ, Methoxatin, BioPQQ

Evidence

Redox cofactor supporting mitochondrial biogenesis and cognitive function. One of few compounds shown to stimulate new mitochondria formation.

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Primary uses

Mitochondrial biogenesis
Cognitive support
Energy
Neuroprotection

How it works

Stimulates PGC-1alpha for new mitochondria
Potent antioxidant (redox cycling)
Nerve growth factor support
Protects neurons from oxidative stress

Dosage

Typical range: 10-20mg daily
Timing: Morning
With food: Optional
Duration: Safe long-term
Special populations: Mitochondrial support, cognitive enhancement

Forms

Capsule
Lozenge

Safety

Common side effects

Well tolerated
Headache rare
Insomnia if taken late

Contraindications

None established

Products containing PQQ (Pyrroloquinoline Quinone)

Top-scoring supplements in our catalog that list PQQ (Pyrroloquinoline Quinone) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

Transparent Labs

Longevity Healthy Aging Complex

Seed

• PM-02™ Sleep + Restore Supplement

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Evidence notes

Unique mitochondrial biogenesis support, growing research

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.