Longevity
PQQ (Pyrroloquinoline Quinone)
Also known as: PQQ, Methoxatin, BioPQQ
B
Evidence
Redox cofactor supporting mitochondrial biogenesis and cognitive function. One of few compounds shown to stimulate new mitochondria formation.
Primary uses
- Mitochondrial biogenesis
- Cognitive support
- Energy
- Neuroprotection
How it works
- Stimulates PGC-1alpha for new mitochondria
- Potent antioxidant (redox cycling)
- Nerve growth factor support
- Protects neurons from oxidative stress
Dosage
- Typical range
- 10-20mg daily
- Timing
- Morning
- With food
- Optional
- Duration
- Safe long-term
- Special populations
- Mitochondrial support, cognitive enhancement
Forms
- Capsule
- Lozenge
Safety
Common side effects
- Well tolerated
- Headache rare
- Insomnia if taken late
Contraindications
- None established
Evidence notes
Unique mitochondrial biogenesis support, growing research
Grade B: Some human trials support key claims; further confirmation needed.
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