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Longevity

Fisetin

Also known as: Fisetin flavonoid

B
Evidence

Strawberry flavonoid with potent senolytic properties. Clears senescent cells.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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The highest-scored Fisetin product in our catalog (86/100). Track dose and overlaps in the app.
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Every Fisetin product we have scored

Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.

Common questions

How much Fisetin should I take?

The typical range is 100-500mg daily or high-dose cycling (up to 20mg/kg for senolytic). Often cycled for senolytic effect

When should I take Fisetin?

Any time. With fat.

Which form of Fisetin is best?

Liposomal — Better absorbed. Other forms in the catalog: Standard.

Is Fisetin safe?

Commonly reported: GI upset. Serious warnings: None known. Safe

Which Fisetin supplement scores highest?

Double Wood Fisetin Supplement, at 86/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.

Primary uses

  • Senolytic
  • Antioxidant
  • Neuroprotection
  • Longevity

How it works

  • Senolytic activity
  • Antioxidant
  • May support brain health

Dosage

Typical range
100-500mg daily or high-dose cycling (up to 20mg/kg for senolytic)
Timing
Any time
With food
With fat
Duration
Often cycled for senolytic effect
Special populations
Longevity protocols, anti-aging

Forms

  • Liposomal
  • Standard

Safety

Common side effects

  • GI upset

Contraindications

  • None known

Products containing Fisetin

Top-scoring supplements in our catalog that list Fisetin on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

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Evidence notes

Potent senolytic flavonoid

Grade B: Some human trials support key claims; further confirmation needed.

Related in Longevity

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.