Iron forms insoluble complexes with levothyroxine, reducing absorption significantly. Can cause treatment failure and persistent hypothyroid symptoms.
Recommendation
Take thyroid medication 4+ hours before iron supplements.
Timing
Thyroid med in morning, iron in evening
Sources
— Annals of Internal Medicine
— PMID: 1982151
Frequently Asked Questions
Can I take iron and thyroid medication together?
Iron reduces levothyroxine absorption. Take thyroid medication 4+ hours before iron supplements.
How should I time iron and thyroid medication?
Thyroid med in morning, iron in evening
Is this interaction dangerous?
This interaction is rated “Warning” by Formulate. Iron forms insoluble complexes with levothyroxine, reducing absorption significantly. Can cause treatment failure and persistent hypothyroid symptoms.
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