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antibiotics and iron

Fluoroquinolones and tetracyclines chelate iron

What's happening

Ciprofloxacin, doxycycline, minocycline, and other fluoroquinolones and tetracyclines form insoluble complexes with iron, dramatically reducing absorption of both the drug and the mineral.

Recommendation

Take iron 2 hours before or 6 hours after these antibiotics to avoid reducing the antibiotic's effectiveness.

Timing

Separate by at least 2 hours before or 6 hours after antibiotic

Sources

  • — Antimicrobial Agents and Chemotherapy
  • — PMID: 2285283

Frequently Asked Questions

Can I take antibiotics and iron together?

Fluoroquinolones and tetracyclines chelate iron. Take iron 2 hours before or 6 hours after these antibiotics to avoid reducing the antibiotic's effectiveness.

How should I time antibiotics and iron?

Separate by at least 2 hours before or 6 hours after antibiotic

Is this interaction dangerous?

This interaction is rated “Warning” by Formulate. Ciprofloxacin, doxycycline, minocycline, and other fluoroquinolones and tetracyclines form insoluble complexes with iron, dramatically reducing absorption of both the drug and the mineral.

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Medical disclaimer. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.