Antacids significantly reduce iron absorption
Iron requires stomach acid for conversion to absorbable Fe2+ form. PPIs and H2 blockers can reduce iron absorption by 65-75%, potentially causing iron deficiency.
Take iron supplements separately from antacids. Consider heme iron sources.
Take iron 2+ hours before antacids, ideally with vitamin C
Antacids significantly reduce iron absorption. Take iron supplements separately from antacids. Consider heme iron sources.
Take iron 2+ hours before antacids, ideally with vitamin C
This interaction is rated “Caution” by Formulate. Iron requires stomach acid for conversion to absorbable Fe2+ form. PPIs and H2 blockers can reduce iron absorption by 65-75%, potentially causing iron deficiency.
The free checker lets you add any combination of supplements and medications at once. Formulate's desktop app goes further — every stack change surfaces interaction alerts automatically.
Medical disclaimer. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.