B-Complex #12
Scored by the Formulate Research Team · Last reviewed July 2026
Overview: Thorne B-Complex #12
B-vitamin complex with extra B12 and folate B-Complex #12 supports energy production and healthy neurological function.* Unlike many multi-B vitamins, it contains the active forms of water-soluble B vitamins.*
Score Breakdown
Three factors carry this score; three more are checked separately and can only take points away. Hover or tap to see what drove each one.
Ingredients per Serving
| Ingredient | Amount |
|---|---|
| CholineCholine Citrate25 systematic reviews · 186 randomised trials | 42 mg |
| Riboflavin25 mg as Riboflavin and 3.6 mg as Riboflavin 5'-Phosphate Sodium9 systematic reviews · 14 randomised trials | 85.8 mg |
| ThiaminThiamin HCl20 systematic reviews · 43 randomised trials | 120 mg |
| Vitamin B12Methylcobalamin141 systematic reviews · 337 randomised trials | 1800 mcg |
| NiacinNiacinamide22 systematic reviews · 99 randomised trials | 240 mg |
| Pantothenic AcidCalcium Pantothenate3 systematic reviews · 27 randomised trials | 135 mg |
| Vitamin B620 mg as Pyridoxine HCl and 3.4 mg as Pyridoxal 5'-Phosphate62 systematic reviews · 142 randomised trials | 70.2 mg |
| Biotin10 systematic reviews · 32 randomised trials | 240 mcg |
| Folate400 mcg as L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt249 systematic reviews · 697 randomised trials | 2001 mcg |
Certifications & Testing
Other Ingredients
Hypromellose (derived from cellulose) capsule, Microcrystalline Cellulose, Calcium Laurate, Silicon Dioxide
Recommended Use
Take 1 capsule one to three times daily or as recommended by your health-care practitioner.
Warnings
ALLERGY WARNING: This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PREGNANCY: If pregnant, consult your health-care practitioner before using this product. INTERACTIONS: 5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic
Frequently Asked Questions
What is Thorne B-Complex #12's Formulate score?
Thorne B-Complex #12 scores 86 out of 100 (grade A-) on Formulate's ingredient-level rubric: clinical evidence, dose accuracy and bioavailability carry the score, while manufacturing, transparency and safety are checked separately and can only deduct.
Is Thorne B-Complex #12 worth it?
Thorne B-Complex #12 scores 86/100 (grade A-). That puts it in Formulate's top tier: its ingredient doses, forms, and label transparency hold up against the clinical evidence, and it carries credible third-party testing. Formulate grades every product with the same automated rubric, so the score reflects the formula — not marketing or sponsorships.
What's in Thorne B-Complex #12?
Each serving contains Choline (42 mg), Riboflavin (85.8 mg), Thiamin (120 mg), Vitamin B12 (1800 mcg), and more. Serving size: 1 Capsule. 60 servings per container.
How do I take b-complex #12?
Take 1 capsule one to three times daily or as recommended by your health-care practitioner.
Who makes B-Complex #12?
B-Complex #12 is made by Thorne. See Formulate's full grade and product lineup for Thorne on its brand page.
Is Thorne B-Complex #12 third-party tested?
Thorne lists the following certifications and testing for this product: Gluten Free, Soy Free, Dairy Free, Vegan, Natural Flavors, Natural Colors, Made in USA, Third-Party Contents Certified, Thorne Verified, GMP Certified.
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Disclosure. Formulate may earn a commission from purchases made through links on this page. Commissions never influence scores — every product is graded by the same automated rubric. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.