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Heart Health

Niacin (Vitamin B3)

Also known as: Nicotinic acid, Vitamin B3 (lipid), Niacin, Vitamin B3

A
Evidence

Niacinamide is a water-soluble B vitamin essential for energy metabolism, DNA repair, and cellular signaling. It supports mental clarity and sustained energy production without the flushing effect associated with nicotinic acid.

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Daily target & upper limit

16 mg / day · UL 35 mg

Niacin (Vitamin B3) has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:

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Primary uses

  • HDL increase
  • Triglycerides
  • LDL reduction
  • Lp(a)
  • energy production
  • mental clarity
  • NAD+ synthesis
  • cognitive function

How it works

  • Increases HDL
  • Lowers triglycerides and LDL
  • May reduce Lp(a)

Dosage

Typical range
500-2000mg daily (titrate up slowly)
Timing
With food, evening
With food
Yes (reduces flushing)
Duration
Ongoing, monitor liver
Special populations
Low HDL, high triglycerides, Lp(a)

Forms

  • Immediate release
  • Extended release
  • No-flush (inositol hexanicotinate)
  • niacinamide· 70/100
  • nicotinamide· 70/100

Safety

Common side effects

  • Flushing (common)
  • GI upset
  • Itching
  • Glucose elevation

Contraindications

  • Active liver disease
  • Peptic ulcer
  • Gout (relative)

Products containing Niacin (Vitamin B3)

Top-scoring supplements in our catalog that list Niacin (Vitamin B3) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

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Evidence notes

Effective for lipids, causes flushing

Grade A: Multiple well-designed human trials support the main claims.

Related in Heart Health

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.