Heart Health
Plant Sterols/Stanols
Also known as: Phytosterols, Sitosterol, Campesterol
Block cholesterol absorption. FDA-approved claim for heart health. Add to diet.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Cholesterol absorption
- LDL reduction
- Heart health
How it works
- Block intestinal cholesterol absorption
- Compete with cholesterol for absorption
- Lower LDL
Dosage
- Typical range
- 2g daily (divided with meals)
- Timing
- With meals (especially fat-containing)
- With food
- Yes (essential)
- Duration
- Ongoing
- Special populations
- Elevated LDL, family history of heart disease
Forms
- Capsules
- Fortified foods
- Powder
Safety
Common side effects
- GI upset
- May reduce carotenoid absorption
Contraindications
- Sitosterolemia (rare genetic condition)
Evidence notes
FDA-approved heart health claim
Grade A: Multiple well-designed human trials support the main claims.
Related in Heart Health
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.