Mineral
Magnesium L-Threonate
Patented form (Magtein) designed to cross blood-brain barrier. Specifically for cognitive enhancement and brain magnesium.
Primary uses
- Cognitive function
- Memory support
- Brain magnesium
- Neuroprotection
How it works
- Threonate enables BBB crossing
- Increases brain Mg levels
- Enhances synaptic plasticity
Dosage
- Typical range
- 1000-2000 mg threonate (144-288 mg elemental)
- Timing
- Divided, some at bedtime
- With food
- Optional
- Duration
- Benefits take 4-6 weeks
- Special populations
- Cognitive concerns
Forms
- Capsule
Safety
Common side effects
- Headache initially
- Drowsiness
Contraindications
- Severe kidney disease
Known interactions
- Cautionwith calcium
High calcium can impair magnesium absorption
- Infowith magnesium
High-dose magnesium may slightly reduce zinc absorption
- Synergywith magnesium
Magnesium needed for vitamin D activation
- Synergywith melatonin
Complementary sleep support
- Synergywith glycine
Both support sleep through different mechanisms
- Cautionwith magnesium
Magnesium may enhance BP lowering effect
Evidence notes
Unique brain penetration
Grade B: Some human trials support key claims; further confirmation needed.
Related in Mineral
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Open the checkerMedical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.