Mineral
Magnesium Malate
Also known as: Mag malate, Dimagnesium malate
Magnesium with malic acid for energy production. Favored for fibromyalgia, chronic fatigue, and muscle pain.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Daily target & upper limit
420 mg / day · UL 350 mgMagnesium Malate has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:
Magnesium Malate dosage reference →Primary uses
- Energy production
- Muscle pain
- Fibromyalgia
- Fatigue
How it works
- Malic acid is Krebs cycle intermediate
- Supports ATP production
- Good bioavailability
Dosage
- Typical range
- 200-400 mg elemental Mg
- Timing
- Morning/daytime
- With food
- Optional
- Duration
- Safe long-term
- Special populations
- Fatigue, fibromyalgia
Forms
- Capsule
- Powder
Safety
Common side effects
- Well tolerated
Contraindications
- Kidney disease
Known interactions
- Cautionwith calcium
High calcium can impair magnesium absorption
- Infowith magnesium
High-dose magnesium may slightly reduce zinc absorption
- Synergywith magnesium
Magnesium needed for vitamin D activation
- Synergywith melatonin
Complementary sleep support
- Synergywith glycine
Both support sleep through different mechanisms
- Cautionwith magnesium
Magnesium may enhance BP lowering effect
Evidence notes
Malic acid adds ATP benefits
Grade B: Some human trials support key claims; further confirmation needed.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.