Fat-soluble vitamins
Vitamin K
Coagulation · bone
Blood clotting and bone matrix protein activation.
What Vitamin K does
Vitamin K is required to gamma-carboxylate clotting factors II, VII, IX, X and bone-matrix proteins like osteocalcin. Two natural forms differ meaningfully: K1 (phylloquinone) from leafy greens primarily supports clotting; K2 (menaquinones, MK-4 through MK-9) from fermented foods and animal products has a longer half-life and is more active in vascular and bone tissue. There's no UL because no toxicity has been observed at high intakes — but warfarin users must keep K intake stable, since K reverses the anticoagulant effect.
Food sources of Vitamin K
Approximate Vitamin K content per serving. Whole-food intake counts toward your daily total alongside any supplemental dose.
| Food | Serving | Vitamin K |
|---|---|---|
| Cooked kale | 1 cup | 1,060 mcg K1 |
| Cooked spinach | 1 cup | 890 mcg K1 |
| Cooked broccoli | 1 cup | 220 mcg K1 |
| Natto (fermented soy) | 1 oz | 300 mcg K2 (MK-7) |
| Hard cheese | 1 oz | 10 mcg K2 |
| Egg yolk | 1 large | 30 mcg K2 |
Signs of Vitamin K deficiency
- ●Easy bruising, prolonged bleeding from minor cuts
- ●Heavy menstrual bleeding, nosebleeds
- ●Elevated prothrombin time (PT/INR) on a coagulation panel
- ●Newborns: hemorrhagic disease of the newborn (why a K injection is given at birth)
Who needs more Vitamin K
Groups and situations where Vitamin K requirements rise or status commonly runs low:
- ●Long-term broad-spectrum antibiotic use — disrupts gut flora that synthesize K2
- ●Fat-malabsorption (cystic fibrosis, biliary atresia, IBD)
- ●Very low intake of leafy greens
- ●Bone-health-focused supplementation may benefit from added MK-7
How Vitamin K appears on labels
Supplement labels list Vitamin K under several names depending on the chemical form used. Any of these on an ingredients panel counts toward your Vitamin K intake:
- vitamin k
- vitamin k1
- vitamin k2
- phylloquinone
- menaquinone
- mk-4
- mk-7
Best supplements for Vitamin K
Top-scoring supplements in our catalog that list Vitamin K on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Deep dive
For mechanism of action, dosing protocols, evidence grade, and interaction warnings on Vitamin K, see the full encyclopedia entry:
Vitamin K encyclopedia entry →Research on Vitamin K
Peer-reviewed studies in our research database that reference Vitamin K. Each entry links to a detailed methodology review.
- Knapen et al., 2017 · Thrombosis and HaemostasisMenaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women
- Violi et al., 2016 · Medicine (Baltimore)Interaction Between Dietary Vitamin K Intake and Anticoagulation by Vitamin K Antagonists: Is It Really True? A Systematic Review
- Yamey et al., 2007 · BMJEffect of fixed-dose vitamin K supplementation on INR stability in warfarin patients
- Couris et al., 2006 · Int J Vitam Nutr ResDietary vitamin K variability affects International Normalized Ratio (INR) coagulation indices
Guides covering Vitamin K
Long-form articles in our guide library that go deeper on Vitamin K — comparisons, protocols, and reviews.
Frequently asked questions
What is the daily target for Vitamin K?
What foods are highest in Vitamin K?
What is the best form of Vitamin K to supplement?
What are the signs of Vitamin K deficiency?
Who is most at risk for low Vitamin K?
Related fat-soluble vitamins
Track your full intake
Formulate's free web app aggregates Vitamin K (and ~40 other nutrients) across every supplement in your stack — flagging underdoses, overlaps, and upper-limit overshoots in one view.
Track your intake free →Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Targets and upper limits are general adult reference values; individual needs vary by age, sex, pregnancy status, and clinical context.







