Vitamin
Vitamin K
Also known as: K1, Phylloquinone, Phytonadione, Vitamin K
A fat-soluble vitamin essential for blood clotting, bone metabolism, and cardiovascular health. Phytonadione (K1) is the plant-derived form found in leafy greens and the primary supplemental form.
Daily target & upper limit
120 mcg / dayVitamin K has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:
Vitamin K dosage reference →Primary uses
- Blood clotting
- Coagulation support
- Blood clotting support
- Bone health and mineralization
- Cardiovascular health
- Protein carboxylation
How it works
- Essential cofactor for clotting factors II, VII, IX, X
- Rapidly cleared from circulation
- Converts to MK-4 in some tissues
Dosage
- Typical range
- 90-120 mcg daily (RDA)
- Timing
- With fat
- With food
- Yes
- Duration
- Usually adequate from diet
- Special populations
- Those on warfarin need consistent intake
Forms
- Tablet
- Phytonadione (K1)· 70/100
- Menaquinone (K2)· 70/100
- Phylloquinone· 70/100
Safety
Common side effects
- Very safe
Contraindications
- Warfarin users (without physician guidance)
- Other vitamin K antagonist anticoagulants
Products containing Vitamin K
Top-scoring supplements in our catalog that list Vitamin K on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.




Known interactions
Evidence notes
Essential for coagulation
Grade A: Multiple well-designed human trials support the main claims.
Cited research for Vitamin K
Clinical studies referenced across Formulate guides that mention vitamin k. Each links to the full study page with PubMed source + the guides that cite it.
- Violi et al. (2016)Medicine (Baltimore)
Interaction Between Dietary Vitamin K Intake and Anticoagulation by Vitamin K Antagonists: Is It Really True? A Systematic Review
- Yamey et al. (2007)BMJ
Effect of fixed-dose vitamin K supplementation on INR stability in warfarin patients
- Couris et al. (2006)Int J Vitam Nutr Res
Dietary vitamin K variability affects International Normalized Ratio (INR) coagulation indices
Related in Vitamin
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Open the checkerMedical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.