Vitamin
Vitamin E
Also known as: Alpha-tocopherol, d-alpha-tocopherol, Tocopherol, Tocotrienol
A fat-soluble antioxidant vitamin that protects cells from free radical damage and supports immune and cardiovascular health. The dl-form (synthetic) is bioequivalent to natural alpha-tocopherol.
Daily target & upper limit
15 mg / day · UL 1000 mgVitamin E has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:
Vitamin E dosage reference →Primary uses
- Antioxidant protection
- Skin health
- Cell membrane integrity
- Cardiovascular health
- Neuroprotection
- Cholesterol support
- Skin protection
- Antioxidant
- Scar healing
- Dry skin
- Immune support
- T-cell function
How it works
- Lipid peroxidation chain breaker
- Cell membrane protection
- Gene expression
Dosage
- Typical range
- 100-400 IU daily
- Timing
- With fat-containing meal
- With food
- Yes
- Duration
- Long-term at moderate doses
- Special populations
- Avoid high doses before surgery
Forms
- Mixed tocopherols softgel
- Full spectrum with tocotrienols
- Annatto-derived
- Palm-derived
- Mixed tocopherols
- d-alpha-tocopherol
- Synthetic (dl-)
- Tocotrienols
- dl-Alpha tocopheryl acetate (synthetic)· 70/100
- d-Alpha tocopherol (natural)· 70/100
- dl-alpha tocopherol (synthetic)· 70/100
- d-α-tocopheryl acetate· 70/100
- d-α-tocopherol· 70/100
Safety
Common side effects
- Well tolerated
Contraindications
- Bleeding disorders
- Pre-surgery
Products containing Vitamin E
Top-scoring supplements in our catalog that list Vitamin E on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Known interactions
Evidence notes
Essential antioxidant vitamin
Grade A: Multiple well-designed human trials support the main claims.
Cited research for Vitamin E
Clinical studies referenced across Formulate guides that mention vitamin e. Each links to the full study page with PubMed source + the guides that cite it.
- Loguercio C, Andreone P, Brisc C, et al. (2012)Free Radical Biology and Medicine
Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease
- Lippman SM, Klein EA, Goodman PJ, et al. (2009)JAMA
Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
Related in Vitamin
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Open the checkerMedical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.