Water-soluble vitamins
Vitamin C
Antioxidant · collagen
Collagen synthesis, antioxidant, immune function.
Upper-limit caution
The Tolerable Upper Intake Level for Vitamin C is 2000 mg per day. Routine intakes above this level — counting food + supplements — raise the risk of adverse effects. Multivitamins, fortified foods, and standalone supplements stack faster than people expect.
What Vitamin C does
Vitamin C is a water-soluble antioxidant and required cofactor for collagen hydroxylase, dopamine beta-hydroxylase, and several other dioxygenases. Humans (along with other primates, guinea pigs, and bats) lost the gene to synthesize it, which is why we need it in the diet. Plasma saturates around 200 mg/day intake — additional intake is excreted. The 2,000 mg upper limit is set on GI tolerance (osmotic diarrhea), not chronic toxicity. Megadose claims for cold prevention are weakly supported; modest reductions in cold duration in habitually deficient people are the most defensible finding.
Food sources of Vitamin C
Approximate Vitamin C content per serving. Whole-food intake counts toward your daily total alongside any supplemental dose.
| Food | Serving | Vitamin C |
|---|---|---|
| Red bell pepper (raw) | 1 medium | 150 mg |
| Orange | 1 medium | 70 mg |
| Kiwifruit | 1 medium | 65 mg |
| Strawberries | 1 cup | 85 mg |
| Cooked broccoli | 1 cup | 100 mg |
| Brussels sprouts (cooked) | 1 cup | 95 mg |
Signs of Vitamin C deficiency
- ●Scurvy: bleeding gums, loose teeth, slow wound healing, perifollicular hemorrhages
- ●Corkscrew hairs, hyperkeratosis on the back of arms
- ●Fatigue, irritability, joint pain
- ●Iron-deficiency anemia (vitamin C enhances non-heme iron absorption)
Who needs more Vitamin C
Groups and situations where Vitamin C requirements rise or status commonly runs low:
- ●Smokers — RDA is ~35 mg higher because of increased oxidative burden
- ●Severe restrictive eating, alcohol use disorder, some hospital-fed patients
- ●Pregnancy and lactation — small bumps to RDA
- ●Wound healing and post-surgical periods (modest evidence)
How Vitamin C appears on labels
Supplement labels list Vitamin C under several names depending on the chemical form used. Any of these on an ingredients panel counts toward your Vitamin C intake:
- vitamin c
- ascorbic acid
- l-ascorbic acid
- sodium ascorbate
- calcium ascorbate
- magnesium ascorbate
- ascorbyl palmitate
Best supplements for Vitamin C
Top-scoring supplements in our catalog that list Vitamin C on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Deep dive
For mechanism of action, dosing protocols, evidence grade, and interaction warnings on Vitamin C, see the full encyclopedia entry:
Vitamin C encyclopedia entry →Research on Vitamin C
Peer-reviewed studies in our research database that reference Vitamin C. Each entry links to a detailed methodology review.
Guides covering Vitamin C
Long-form articles in our guide library that go deeper on Vitamin C — comparisons, protocols, and reviews.
- Roundup · 10 min readBest Vitamin C Supplements 2026: Form, Dose, and What Actually Works
- Guide · 12 min readElectrolytes Guide 2026: Evidence-Based Sodium, Potassium & Magnesium
- Guide · 9 min readMagnesium Glycinate vs Citrate vs Oxide: Which Form Actually Absorbs?
- Roundup · 9 min readBest Magnesium Supplements 2026, Ranked by Clinical Evidence
- Protocol · 10 min readBest Sleep Supplement Protocol 2026: Clinical Evidence Stack
Frequently asked questions
What is the daily target for Vitamin C?
What foods are highest in Vitamin C?
What is the best form of Vitamin C to supplement?
What are the signs of Vitamin C deficiency?
Who is most at risk for low Vitamin C?
Related water-soluble vitamins
Track your full intake
Formulate's free web app aggregates Vitamin C (and ~40 other nutrients) across every supplement in your stack — flagging underdoses, overlaps, and upper-limit overshoots in one view.
Track your intake free →Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Targets and upper limits are general adult reference values; individual needs vary by age, sex, pregnancy status, and clinical context.







