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rhodiola and ssri

Rhodiola may have mild MAOI effects

What's happening

Rhodiola rosea may have mild MAO-inhibiting properties. Combined with SSRIs, theoretical risk of serotonin syndrome, though clinical reports are limited.

Recommendation

Use cautiously with SSRIs. Start with low doses and monitor mood.

Timing

Start with low doses; watch for agitation, anxiety

Sources

  • Phytomedicine
  • PMID: 22643881

Frequently Asked Questions

Can I take rhodiola and ssri together?

Rhodiola may have mild MAOI effects. Use cautiously with SSRIs. Start with low doses and monitor mood.

How should I time rhodiola and ssri?

Start with low doses; watch for agitation, anxiety

Is this interaction dangerous?

This interaction is rated “Caution” by Formulate. Rhodiola rosea may have mild MAO-inhibiting properties. Combined with SSRIs, theoretical risk of serotonin syndrome, though clinical reports are limited.

Want to check your whole stack?

The free checker lets you add any combination of supplements and medications at once. Formulate's desktop app goes further — every stack change surfaces interaction alerts automatically.

Medical disclaimer. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.