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Nootropic

Rhodiola rosea

Also known as: Rhodiola rosea Extract, Rhodiola, Golden Root, Roseroot

A
Evidence

Rhodiola rosea is a traditional adaptogenic herb used to support stress resilience, mental fatigue, and mood. Clinical evidence shows modest benefits for stress-related fatigue and cognitive performance, though effects are generally moderate in magnitude.

Primary uses

  • Mental fatigue
  • Stress resilience
  • Focus
  • Mood
  • Stress resilience and adaptation
  • Mental fatigue and cognitive performance
  • Mood support
  • Physical endurance and recovery

How it works

  • Inhibits MAO-A and MAO-B
  • Modulates cortisol
  • Increases stress resistance

Dosage

Typical range
200-600 mg daily
Timing
Morning (can be stimulating)
With food
Optional
Duration
Cycle: 3 weeks on, 1 week off
Special populations
High stress, mental fatigue

Forms

  • Standardized extract
  • SHR-5 extract
  • Root powder· 70/100
  • Capsule· 70/100
  • Tablet· 70/100
  • Liquid extract· 70/100

Safety

Common side effects

  • Insomnia if late
  • Jitteriness
  • Dry mouth

Contraindications

  • Bipolar (may trigger mania)

Known interactions

Evidence notes

Well-studied adaptogen for mental performance

Grade A: Multiple well-designed human trials support the main claims.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.