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Nootropic

Rhodiola rosea

Also known as: Rhodiola rosea Extract, Rhodiola, Golden Root, Roseroot

A
Evidence

Rhodiola rosea is a traditional adaptogenic herb used to support stress resilience, mental fatigue, and mood. Clinical evidence shows modest benefits for stress-related fatigue and cognitive performance, though effects are generally moderate in magnitude.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

  • Mental fatigue
  • Stress resilience
  • Focus
  • Mood
  • Stress resilience and adaptation
  • Mental fatigue and cognitive performance
  • Mood support
  • Physical endurance and recovery

How it works

  • Inhibits MAO-A and MAO-B
  • Modulates cortisol
  • Increases stress resistance

Dosage

Typical range
200-600 mg daily
Timing
Morning (can be stimulating)
With food
Optional
Duration
Cycle: 3 weeks on, 1 week off
Special populations
High stress, mental fatigue

Forms

  • Standardized extract
  • SHR-5 extract
  • Root powder· 70/100
  • Capsule· 70/100
  • Tablet· 70/100
  • Liquid extract· 70/100

Safety

Common side effects

  • Insomnia if late
  • Jitteriness
  • Dry mouth

Contraindications

  • Bipolar (may trigger mania)

Products containing Rhodiola rosea

Top-scoring supplements in our catalog that list Rhodiola rosea on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

Thorne
Rhodiola
92
BulkSupplements
Rhodiola Extract (3% Salidroside) Powder
91
Thorne
Emotion Balance Support
87
Thorne
Daily Greens Plus
79
See all products →

Known interactions

Evidence notes

Well-studied adaptogen for mental performance

Grade A: Multiple well-designed human trials support the main claims.

Cited research for Rhodiola rosea

Clinical studies referenced across Formulate guides that mention rhodiola rosea. Each links to the full study page with PubMed source + the guides that cite it.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.