Nootropic
Coffee Fruit Extract
Also known as: CognatiQ, NeuroFactor, Coffeeberry, Coffee Berry
Extract from the fruit surrounding coffee beans. Shown to significantly increase BDNF (brain-derived neurotrophic factor) levels, supporting neuroplasticity and cognitive function.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Coffee Fruit Extract product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Pure Encapsulations CaffPhenol | 88 A | $0.98 |
| 2 | Thorne Brain Factors | 84 A- | $1.70 |
| 3 | Allergy Research Group Advanced NeuroPlus | 78 B+ | $2.97 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Coffee Fruit Extract should I take?
The typical range is 100-200 mg daily. Effects may build over weeks
When should I take Coffee Fruit Extract?
Morning or early afternoon. Optional.
Which form of Coffee Fruit Extract is best?
Capsule — Standardized extract. Other forms in the catalog: Powder.
Is Coffee Fruit Extract safe?
Commonly reported: Mild stimulation (contains some caffeine). Serious warnings: None known. No concerns
Which Coffee Fruit Extract supplement scores highest?
Pure Encapsulations CaffPhenol, at 88/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- BDNF support
- Cognitive function
- Neuroprotection
- Brain health
How it works
- Increases BDNF (brain-derived neurotrophic factor)
- Supports neuroplasticity
- Polyphenol antioxidant activity
- May support neuron growth and survival
Dosage
- Typical range
- 100-200 mg daily
- Timing
- Morning or early afternoon
- With food
- Optional
- Duration
- Effects may build over weeks
- Special populations
- Cognitive support focus
Forms
- Capsule
- Powder
Safety
Common side effects
- Mild stimulation (contains some caffeine)
Contraindications
- Caffeine sensitivity
Products containing Coffee Fruit Extract
Top-scoring supplements in our catalog that list Coffee Fruit Extract on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Multiple studies showing BDNF increase; cognitive benefits emerging
Grade B: Some human trials support key claims; further confirmation needed.
Related in Nootropic
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.