Nootropic
Lion's Mane Mycelium
Also known as: Hericium erinaceus, Yamabushitake, Bearded tooth mushroom, Hou Tou Gu
Lion's Mane mushroom mycelium contains bioactive compounds (hericenones and erinacines) studied for potential cognitive and neurological support. A growing body of research, primarily in Asia, suggests benefits for brain health, though larger Western trials are needed.
Primary uses
- Cognitive support
- Nerve growth factor (NGF) support
- Immune support
How it works
- Hericenone and erinacine compounds that may stimulate NGF production
- Polysaccharide immune modulation
- Potential neuroprotection
Dosage
- Typical range
- 1,000-3,000 mg daily (mycelium form)
- Timing
- With meals
- With food
- Recommended for optimal absorption
- Duration
- Consistent daily use for 4-8 weeks may be needed for cognitive effects
- Special populations
- Safe for most adults; pregnant/nursing should consult provider
Forms
- Mycelium on rice biomass· 70/100
- Fruiting body extract· 70/100
- Capsule· 70/100
Safety
Common side effects
- Rare: mild digestive upset
- Rare: allergic reactions in mushroom-sensitive individuals
Contraindications
- Mushroom allergies
- Bleeding disorders (theoretical)
Evidence notes
Multiple animal studies and several preliminary human trials show promise for cognitive and neuroprotective effects. Evidence is stronger than most medicinal mushrooms but still developing. Some human studies show cognitive benefits in older adults with mild cognitive impairment.
Grade B: Some human trials support key claims; further confirmation needed.
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