Nootropic

Lion's Mane Mushroom

Also known as: Hericium erinaceus, Yamabushitake, Lion's Mane (Hericium erinaceus), Bearded tooth mushroom

Evidence

Brain-supporting mushroom that also has immune-modulating and gut-healing properties through nerve growth factor stimulation.

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Primary uses

Cognitive function
Memory
Nerve regeneration
Neuroprotection
Cognitive support
Gut health
Immune modulation

How it works

Stimulates NGF synthesis
Promotes neurogenesis
Supports myelin production

Dosage

Typical range: 500-3000 mg daily
Timing: Any time; may take weeks for effects
With food: Optional
Duration: 8+ weeks for cognitive benefits
Special populations: Cognitive decline, students

Forms

Fruiting body extract
Mycelium on grain
Dual extract
Fresh/culinary

Safety

Common side effects

Mild GI upset
Itchy skin (rare)

Contraindications

Mushroom allergy

Products containing Lion's Mane Mushroom

Top-scoring supplements in our catalog that list Lion's Mane Mushroom on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

Thorne

Ginseng Plus

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Evidence notes

Unique NGF-stimulating properties

Grade B: Some human trials support key claims; further confirmation needed.

Cited research for Lion's Mane Mushroom

Clinical studies referenced across Formulate guides that mention lion's mane mushroom. Each links to the full study page with PubMed source + the guides that cite it.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.