Nootropic

Adrafinil

Also known as: Olmifon

Evidence

Prodrug converting to modafinil in the liver. Unscheduled in many countries but requires liver monitoring.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

Wakefulness
Focus
Alertness

How it works

Converts to modafinil in liver
Similar mechanism once converted

Dosage

Typical range: 300-600 mg daily
Timing: Morning
With food: Optional
Duration: Not for daily long-term use
Special populations: Occasional use only

Forms

Capsules
Powder

Safety

Common side effects

Same as modafinil
Liver enzyme elevation

Contraindications

Liver disease

Evidence notes

Prodrug - liver concerns with long-term use

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.