Nootropic
Acetyl-L-Carnitine (ALCAR)
Also known as: ALC, Acetyl L-Carnitine HCl, ALCAR, Acetyl-L-Carnitine
Acetyl L-Carnitine is a form of carnitine that crosses the blood-brain barrier and supports mitochondrial energy production and acetylcholine synthesis. It has shown modest benefits for cognitive function and energy metabolism in some studies, with stronger evidence in elderly populations and carnitine-deficient states.
Primary uses
- Brain energy
- Memory
- Neuroprotection
- Mood
- Cognitive support
- Energy and fatigue
- Brain health and neuroprotection
- Age-related cognitive decline
How it works
- Crosses BBB
- Acetyl donor for acetylcholine
- Supports mitochondrial function in brain
Dosage
- Typical range
- 500-2000 mg daily
- Timing
- Morning (mildly stimulating)
- With food
- Optional
- Duration
- Safe long-term
- Special populations
- Cognitive aging, depression
Forms
- Capsules
- Powder
- HCl salt (hydrochloride)· 70/100
- Tablets· 70/100
Safety
Common side effects
- GI upset
- Fishy odor
- Insomnia if late
Contraindications
- Seizure disorders (caution)
Evidence notes
Brain-penetrating carnitine
Grade B: Some human trials support key claims; further confirmation needed.
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