omega-3 and warfarin

Mentions warfarin · 2025

Impact of Ginkgo biloba drug interactions on bleeding risk and coagulation profiles

Primary literature · Observational study

Ginkgo + aspirin: bleeding risk OR 1.12 (95% CI 1.07-1.18, p<0.001); abnormal coagulation OR 1.48 (95% CI 1.32-1.66, p<0.001). Ginkgo + clopidogrel: bleeding risk OR 1.10 (95% CI 1.05-1.15, p<0.001); abnormal coagulation OR 1.58 (95% CI 1.40-1.77, p<0.001). Ginkgo + warfarin: NO statistically significant correlation with bleeding or coagulation.

Mentions omega-3 · 2020

Effect of High-Dose Omega-3 Fatty Acids vs Corn Oil on Major Adverse Cardiovascular Events (STRENGTH)

Nicholls et al. · JAMA

STRENGTH trial (n=13,078). High-dose EPA/DHA did not reduce cardiovascular events — contradicts REDUCE-IT finding.

Mentions omega-3 · 2019

Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association

Skulas-Ray et al. · Circulation

AHA science advisory on triglyceride-lowering effects of 2–4g/day EPA+DHA — typically a 20–30% reduction.

Mentions omega-3 · 2019

Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia (REDUCE-IT)

Bhatt DL, Steg PG, Miller M, et al. · New England Journal of Medicine

Double-blind RCT (n=8,179) found high-dose EPA (4g/day) reduced ischemic events by 25% vs placebo in patients with elevated triglycerides on statins — the most convincing cardiovascular benefit data for omega-3s.

Mentions omega-3 · 2019

Efficacy of omega-3 PUFAs in depression: a meta-analysis

Liao et al. · Translational Psychiatry

EPA-dominant formulas (≥60% EPA) were significantly more effective for depression than DHA-dominant ones.

Mentions omega-3 · 2018

Associations of omega-3 fatty acid supplement use with cardiovascular disease risks: meta-analysis of 10 trials involving 77,917 individuals

Aung et al. · JAMA Cardiology

Large meta-analysis examining cardiovascular outcomes of omega-3 supplementation across 77,917 participants.

Roundup

Best Omega-3 Supplements 2026, Ranked by Clinical Evidence

Learn to decode EPA+DHA labels, absorption forms, and oxidation scores. We ranked 8 omega-3 supplements using clinical evidence — no guesswork.