N-acetylcysteine supplies the cysteine needed to synthesize glutathione, the body's primary intracellular antioxidant. Oral glutathione has poor bioavailability, so raising glutathione via NAC is usually more effective.
Recommendation
600-1200mg NAC daily is typically more effective than oral glutathione for raising cellular glutathione levels.
Timing
Take NAC on an empty stomach
Sources
— Biochimica et Biophysica Acta
— PMID: 23747562
Frequently Asked Questions
Can I take glutathione and nac together?
NAC is the rate-limiting precursor to glutathione. 600-1200mg NAC daily is typically more effective than oral glutathione for raising cellular glutathione levels.
How should I time glutathione and nac?
Take NAC on an empty stomach
Is this interaction dangerous?
This interaction is rated “Synergy” by Formulate. N-acetylcysteine supplies the cysteine needed to synthesize glutathione, the body's primary intracellular antioxidant. Oral glutathione has poor bioavailability, so raising glutathione via NAC is usually more effective.
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