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Performance

HMB (Beta-Hydroxy Beta-Methylbutyrate)

Also known as: Beta-Hydroxy Beta-Methylbutyrate, HMB (β-Hydroxy β-Methylbutyrate), HMB-Ca, HMB-FA

B
Evidence

Leucine metabolite that may reduce muscle protein breakdown. Most useful during caloric restriction or for beginners.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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The highest-scored HMB (Beta-Hydroxy Beta-Methylbutyrate) product in our catalog (92/100). Track dose and overlaps in the app.
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Every HMB (Beta-Hydroxy Beta-Methylbutyrate) product we have scored

Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.

Common questions

How much HMB (Beta-Hydroxy Beta-Methylbutyrate) should I take?

The typical range is 3 g daily in divided doses. Safe long-term

When should I take HMB (Beta-Hydroxy Beta-Methylbutyrate)?

Before/after workouts and with meals. Optional.

Which form of HMB (Beta-Hydroxy Beta-Methylbutyrate) is best?

HMB-FA (free acid) — Faster absorption. Other forms in the catalog: HMB-Ca (calcium salt).

Is HMB (Beta-Hydroxy Beta-Methylbutyrate) safe?

Commonly reported: Well tolerated. Serious warnings: None. Safe

Which HMB (Beta-Hydroxy Beta-Methylbutyrate) supplement scores highest?

NOW Foods HMB, at 92/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.

Primary uses

  • Muscle preservation
  • Recovery
  • Strength (beginners)

How it works

  • Reduces muscle protein breakdown
  • May increase protein synthesis
  • Metabolite of leucine

Dosage

Typical range
3 g daily in divided doses
Timing
Before/after workouts and with meals
With food
Optional
Duration
Safe long-term
Special populations
Cutting phase, beginners, elderly

Forms

  • HMB-FA (free acid)
  • HMB-Ca (calcium salt)

Safety

Common side effects

  • Well tolerated

Contraindications

  • None

Products containing HMB (Beta-Hydroxy Beta-Methylbutyrate)

Top-scoring supplements in our catalog that list HMB (Beta-Hydroxy Beta-Methylbutyrate) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

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Evidence notes

Helps prevent muscle loss

Grade B: Some human trials support key claims; further confirmation needed.

HMB (Beta-Hydroxy Beta-Methylbutyrate) compared head-to-head

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.