Performance

Agmatine Sulfate

Also known as: Agmatine sulfate

Evidence

Arginine metabolite with nitric oxide and pain-modulating effects. Enhances pumps.

Primary uses

Pump
Pain modulation
Mood
Insulin sensitivity

How it works

Modulates nitric oxide synthases
NMDA receptor effects
Endorphin release

Dosage

Typical range: 500-2000mg
Timing: Pre-workout
With food: Either
Duration: Daily use studied
Special populations: Pump seekers, neuropathic pain

Forms

Powder
Capsule

Safety

Common side effects

GI upset
May affect blood pressure

Contraindications

None known

Evidence notes

Emerging research, promising for pumps and mood

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.