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Performance

L-Citrulline / Citrulline Malate

Also known as: L-Citrulline, Citrulline malate

A
Evidence

Converts to arginine, boosting nitric oxide. Enhances blood flow and reduces fatigue.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Daily target & upper limit

6 g / day

L-Citrulline / Citrulline Malate has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:

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Primary uses

  • Pump
  • Endurance
  • Blood flow
  • Fatigue reduction

How it works

  • Converts to arginine (better than direct arginine)
  • Increases nitric oxide
  • Reduces lactate and ammonia

Dosage

Typical range
6-8g L-citrulline or 8-10g citrulline malate
Timing
30-60 min pre-workout
With food
Either
Duration
Acute effects, daily dosing beneficial
Special populations
Athletes, cardiovascular support

Forms

  • L-Citrulline
  • Citrulline malate 2:1

Safety

Common side effects

  • GI upset at high doses

Contraindications

  • None known

Products containing L-Citrulline / Citrulline Malate

Top-scoring supplements in our catalog that list L-Citrulline / Citrulline Malate on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

BulkSupplements
L-Citrulline Powder
91
Transparent Labs
BULK Pre-Workout
90
See all products →

Evidence notes

Well-established for performance

Grade A: Multiple well-designed human trials support the main claims.

Related in Performance

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.