Performance
Nitrosigine
Also known as: Inositol-stabilized arginine silicate
Patented arginine silicate complex with superior absorption. Fast-acting pump ingredient.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Pump
- Blood flow
- Cognitive function
How it works
- Enhanced arginine bioavailability
- Sustained NO increase
- Cognitive benefits reported
Dosage
- Typical range
- 750-1500mg
- Timing
- 30 min pre-workout
- With food
- Either
- Duration
- Acute effects
- Special populations
- Pump and cognitive focus
Forms
- Capsule or powder
Safety
Common side effects
- Generally well tolerated
Contraindications
- Same as arginine
Evidence notes
Good evidence for blood flow and cognition
Grade B: Some human trials support key claims; further confirmation needed.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.