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Performance

BCAAs

Also known as: Leucine, Isoleucine, Valine, 2:1:1 ratio

B
Evidence

A branched-chain amino acid blend in a 2:1:1 leucine-to-isoleucine-to-valine ratio, formulated in instantized (micronized) form for improved solubility. BCAAs support muscle protein synthesis and may reduce exercise-induced fatigue, though whole protein sources provide comparable benefits at lower cost.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

Add Thorne Creatine + BCAAs to your stack — free
The highest-scored BCAAs product in our catalog (92/100). Track dose and overlaps in the app.
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Every BCAAs product we have scored

Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.

Common questions

How much BCAAs should I take?

The typical range is 5-10g. During training periods

When should I take BCAAs?

Intra-workout or fasted training. Either.

Which form of BCAAs is best?

Powder — Flavored options. Other forms in the catalog: Capsule, Capsules, Tablets, drinks, 2:1:1 ratio blend.

Is BCAAs safe?

Commonly reported: Generally well tolerated. Serious warnings: None. Normal amino acid considerations

Which BCAAs supplement scores highest?

Thorne Creatine + BCAAs, at 92/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.

Primary uses

  • Muscle preservation
  • Intra-workout
  • Fatigue reduction
  • Muscle protein synthesis
  • Exercise recovery
  • Muscle preservation during caloric deficit
  • Reduction of exercise-induced fatigue
  • reduce muscle breakdown (anticatabolic)
  • endurance performance
  • post-workout recovery

What systematic reviews concluded

Outcomes that systematic reviews of BCAAs reached a verdict on: 1 with a benefit, 1 unclear. Each is quoted from a review and linked to it on PubMed. How these were read.

Reviews found a benefit (1)

Benefitmuscle recovery
“Intake of BCAA favors post-exercise muscle recovery and may improve muscle function.” PMID 33586928
Every supplement reviewed for exercise recovery →

Not enough to say: muscle function.

How it works

  • Leucine triggers mTOR
  • May reduce muscle breakdown
  • Incomplete without other EAAs

Dosage

Typical range
5-10g
Timing
Intra-workout or fasted training
With food
Either
Duration
During training periods
Special populations
Fasted training, low protein meals

Forms

  • Powder
  • Capsule
  • Capsules· 70/100
  • Tablets· 70/100
  • drinks· 70/100
  • 2:1:1 ratio blend· 70/100

Safety

Common side effects

  • Generally well tolerated

Contraindications

  • MSUD (rare genetic)

Products containing BCAAs

Top-scoring supplements in our catalog that list BCAAs on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

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Evidence notes

Superseded by EAAs or adequate protein, but still useful

Grade B: Some human trials support key claims; further confirmation needed.

BCAAs compared head-to-head

Related in Performance

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.