Amino Acid
Glycine (Longevity Dose)
Also known as: Glycine, Aminoacetic acid
Simplest amino acid with emerging longevity benefits at higher doses. Supports glutathione, collagen, sleep, and may mimic methionine restriction.
Daily target & upper limit
3 g / dayGlycine (Longevity Dose) has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:
Glycine (Longevity Dose) dosage reference →Primary uses
- Longevity
- Sleep
- Glutathione support
- Collagen synthesis
How it works
- Glutathione precursor
- Collagen building block
- May mimic methionine restriction
- Inhibitory neurotransmitter
Dosage
- Typical range
- 3-15g daily for longevity; 3g for sleep
- Timing
- Before bed for sleep; divided for longevity
- With food
- Optional
- Duration
- Safe long-term
- Special populations
- Sleep, longevity, glutathione support
Forms
- Powder
- Capsules
Safety
Common side effects
- Sweet taste
- Soft stools at high doses
Contraindications
- None
Products containing Glycine (Longevity Dose)
Top-scoring supplements in our catalog that list Glycine (Longevity Dose) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
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Evidence notes
Traditional uses plus emerging longevity research
Grade B: Some human trials support key claims; further confirmation needed.
Cited research for Glycine (Longevity Dose)
Clinical studies referenced across Formulate guides that mention glycine (longevity dose). Each links to the full study page with PubMed source + the guides that cite it.
- Kawai N, Sakai N, Okuro M, et al. (2015)Neuropsychopharmacology
The sleep-promoting and hypothermic effects of glycine are mediated by NMDA receptors in the suprachiasmatic nucleus
- Bannai and Kawai (2012)Journal of Pharmacological Sciences
New therapeutic strategy for amino acid medicine: glycine improves the quality of sleep
- Yamadera W, Inagawa K, Chiba S, et al. (2007)Sleep and Biological Rhythms
Glycine ingestion improves subjective sleep quality in human volunteers
Related in Amino Acid
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